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KMID : 0361620080430020193
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Journal of the Korean Orthopaedic Association
2008 Volume.43 No. 2 p.193 ~ p.199
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The Results of Autologous Chondrocyte Implantation with a Concomitant Injury
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Jeong Bi-O
Yoon Kyoung-Ho
Bae Dae-Kyung
Moon Jee-Soo
Song Sang-Joon
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Abstract
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Purpose: To evaluate the results of autologous chondrocyte implantation with a concomitant injury.
Materials and Methods: Sixty-seven chondral defects (39 cases, 36 patients), which were treated with autologous chondrocyte implantation, were analyzed with a minimum follow-up of 2 years. The cases were divided into the following five groups: 4 cases of a single chondral defect (group I), 3 cases of multiple chondral defects (group II), 5 cases of osteochondritis dissecans (group III), 9 cases of a single chondral defect with a concomitant injury (group IV), and 18 cases of multiple chondral defects with a concomitant injury (group V). The clinical outcomes were evaluated using the International Knee Documentation Committee (IKDC) subjective and objective scores and the International Cartilage Repair Society (ICRS) functional evaluation system. Arthroscopic examinations were performed on 12 cases and 21 chondral defects.
Results: The mean IKDC subjective score was 39.8 preoperatively, which improved to 64.1 postoperatively, and the IKDC objective score was C in 54% and D in 46%, which improved to A in 74%, B in 23% and C in 3%. The ICRS functional evaluation system was III in 82% of cases, and IV in 18% preoperatively, which improved to I in 15% and II in 85%, postoperatively. At the arthroscopic evaluation, the results of the ICRS system were I in 9%, II in 67%, and III in 24%. There was no significant difference between the single chondral defect and chondral defects with a concomitant injury.
Conclusion: In the treatment of the multiple chondral defects with a concomitant injury, autologous chondrocyte implantation produced similar excellent clinical results to those of a single chondral defect.
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KEYWORD
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Knee, Chondral defect, Autologous chondrocyte implantation
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